Functional Magnetic Resonance Imaging
Computers for lab exercises are available in rooms 251.
Departments of Psychiatry, Neurobiology, and Psychology
Brain Imaging and Analysis Center
email: phone: 681-9527
Given the size of the class, office hours will be by appointment.
This course is intended to provide a comprehensive and rigorous introduction to the technique of functional magnetic resonance imaging (fMRI). Students will learn the basic physics underlying MRI, the biological principles of fMRI, the principles of experimental design, the processing steps associated with data analysis, and the use of available software packages.
Each week’s session will be composed of a lecture and laboratory. Each part will be led by one or more BIAC faculty members. Where possible, the laboratory topics will be flexible so that students with more experience can explore the issues covered in more detail.
As this is a graduate course, grades will reflect a certification of training, rather than a competition between students. Therefore, all grades can be raised to “E” by demonstrating understanding of the material. Grades will be based on participation in course sessions, completion of laboratory exercises, one take-home test at the middle of the semester, and a final practicum research project.
Auditors are welcome (and encouraged) to take the course, but regular attendance and participation is required. It is strongly recommended that auditors attend both the lecture and laboratory sessions, if possible, as they will be designed to complement each other.
Please note: you must have a BIAC login to access the readings. We apologize for the inconvenience. Also, additional readings and lecture notes will appear here as the semester progresses. If you want a printed copy of the handouts, we recommend opening the Powerpoint version and selecting Print As: Handout from the Print dialog. This will save ink and paper.
Laboratory: Visit to MR Scanner, Real-time fMRI (Voyvodic)
Readings: "An Introduction...", Matthews
Readings: Buxton Ch. 4,7
Laboratory: Creating a MR Image (exercises)
9/25 Lecture: MR Physics: Pulse Sequences and Contrast (Song)
Laboratory: Analysis of functional data: Introduction (exercises)
Readings: Buxton, Ch. 8,11
Laboratory: Working with fMRI datasets
Laboratory: Limits on Resolution, Understanding refractory effects (exercises)
Laboratory: Effects of sampling upon functional images (exercises)
Readings: Buxton, Ch. 12; Huettel (2001)
Readings: To be announced
Laboratory: Comparison of Different Design Types
Readings: Buxton, Ch. 19
Readings: Buxton, Ch. 18
11/20 Lecture: Functional Brain Anatomy (McCarthy)
Readings: To be announced
11/27 Lecture: Advanced
functional MR imaging techniques (Song)
[To be rescheduled]
Laboratory: To be announced
Readings: Buxton, Ch. 9, 13-15